What's the best Covid Vaccine?

I was recently vaccinated with J&J, a single-shot anti-COVID vaccine. But they couldn't tell me how long it will protect me. What do you think? When will the next shot be necessary?

 

Every manufacturer is keeping an eye on antibodies and they will take that information to the CDC to see when or if boosters are needed....Largest problem will be the variants and how they continue to change and morf
If I had a choice I would be Moderna. OMHO....But I have had my 2 Phizers since March.

 

Did you do a search on this forum? I know this has been discussed by several people including current concerns about Delta and Lambda variants.

How are you feeling? I hope you get through it without any major side-effects.

 

I like the answer I've heard in the past: "The one that's in your arm".

 

It's not a small number. Current science shows that "vaccines" only seem to be about 50% effective at protecting you from Delta and Pfizer only comes in at 42%. And, yes, even though they don't protect you much from getting Delta, the vaccines do seem very effective at greatly reducing the number of hospitalizations and deaths, but you can expect to feel sick, very sick if you are one of the 50%.

 

Jack Daniels

 

Now THAT is a load of bunkum

Read Centerfields excellent post on this

 

Yep! Go for it mate - people who refuse to vaccinate whilst Delta is on the go….. well I think of it as evolution in action

 

What post of mine, and on what? I'm not following what generated this response; must be someone I have on Ignore.

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@pitbull

To respond to the OP, I'll be long because the issue is more complex than people realize.

You took the J&J. The J&J is a single dose shot. They actually are studying a 2-dose regimen but at the time when they asked the FDA for emergency use authorization, that part of their trials wasn't ready yet (and presently, still isn't), so they just applied for the single dose regimen.

Their trial for the 2-dose regimen is called ENSEMBLE 2. It has finished recruiting. They have recruited 31,836 participants; half of them are getting the two shots separated by 57 days, and the other half are taking placebos. So once they conclude, we'll learn if you should get another J&J shot two months after your first one, in case the FDA authorizes this regimen, and the CDC agrees. There's been hints that the CDC does not want to agree; they prefer that the J&J remains a single-dose shot for various reasons that I won't discuss, at this time. Still, people say that if the results of the ENSEMBLE 2 end up being excellent and much better than the 1-dose regimen, and the FDA approves this 2-dose regimen, it will be hard for the CDC to remain obstinate and deny recommendation (in the United States, for a vaccine to legally get into a patient's arm under an EUA - emergency use authorization, both the FDA authorization and the CDC recommendation are needed).

There are hints that the Pfizer shot's protection against the now dominant Delta variant fades about 5-6 months after the second shot (one piece of evidence, for example: people who took the last Pfizer shot more than 5 months ago have been shown to be twice as likely to catch the Delta in what we call a breakthrough infection, as compared to those who took the last shot less than 5 months ago). So Pfizer is recommending a booster shot after 6 months.

There are hints that the Moderna shot lasts longer than Pfizer, against the Delta.

If this is confirmed, I'd say that Moderna is currently the best vaccine.

OK, so, you took the J&J. If you are in the United States or in Israel, Germany, the UK, or France, these countries have all authorized booster shots already, for the more vulnerable population (they have started with the immunocompromised, that is, people with cancer, people who had transplants, people who take certain drugs to calm down their immune system due to auto-immune diseases, etc.).

It is expected that the indication for booster shots will broaden, and eventually everybody will qualify for one.

So, at that point, should you get a second J&J?

Actually, I'd recommend an mRNA vaccine booster (Moderna preferably, or Pfizer if Moderna is not available). Experts at the Mayo Clinic and at Beth Israel agree with me. It seems like the mixing-and-matching strategy might be a good one. Why? Because the J&J and the AstraZeneca tend to be more robust in fostering cellular immunity, while the Moderna and Pfizer tend to me more robust for humoral immunity.

So by mixing and matching you might strengthen even more your immune system's preparedness to deal with the SARS-CoV-2 in its recent and more dangerous variants.

This is not, however, the FDA's and the CDC's position. They recommend boosters with the same vaccine you had before. They are not considering boosters for the J&J at this time.

On the other hand, the FDA is said to be very close to issuing FULL APPROVAL (no long merely an EUA) for both the Pfizer and the Moderna. It is supposed to happen in no longer than 4-5 weeks from now.

Why is this important?

Because once it's fully approved, a doctor can simply recommend (prescribe) the shot, and you take the prescription to a pharmacy and they give it to you, regardless of eligibility criteria. It becomes a "prescribable" vaccine (I made this word up).

So, if you decided to get a booster of Moderna on top of your J&J, or Pfizer, you'd be able to get one in case a physician prescribed one for you.

Should you then go and get a second Moderna or Pfizer shot on top of your J&J + booster? At this point, no. People who are considered to be fully vaccinated (either two doses of Pfizer or Moderna, or one dose of the J&J) are not supposed to get more than one booster, yet. Why? Because we don't know if doubling up like this is safe, yet.

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Could you use the same mechanism of a "prescribable" J&J shot for a second J&J dose even if the CDC doesn't recommend it? Not at this time. the FDA is NOT considering full approval for the J&J, yet. Full approval is only expected for Pfizer and Moderna.

It will take long for the J&J to get full approval because they haven't even concluded their Phase III ENSEMBLE 2 trial yet. The FDA requires six months of safety data after the last participant of a phase 3 trial completed the last shot. Then the FDA takes a while to consider it. It could be one year before the J&J gets full approval.

 

Darwin Award.

 

They'll Darwin Award themselves.

 

You were not vaccinated in the traditional legal and medical sense, you were injected with an mRNA device that also contains Graphene Oxide.

Gathering data during these last 8 months, and observing high rates of injection being followed by high rates of positive tests, and observing so many people who've been injected subsequently becoming sick with symptoms, it's safe to say the clot shots don't protect anybody from anything, even as they expose them to all sorts of other unhealthy situations, mostly blood related.

Best of luck to you.

 

I don’t work on a ship.

 

So, you would rather have me ignore the science and listen to Centerfield?

 

I took the Moderna vaccine, which appears to be the most effective, with the least negatives and the most durable efficacy. (about 75% up to six months after being fully vaccinated) I seem to hear more negatives coming from the Pfizer and J&J vaccines. The ones the so-called "experts" were pushing on this forum.

 

Centerfield IS quoting the science - I don’t know where you are getting your bunkum from

 

No and unless you live on a deserted island then you have a social responsibility

 

https://www.medrxiv.org/content/10.1101/2021.08.06.21261707v1

 

I read this information

The summary is quite succinct:

Its hard to what science you are suggesting what science CenterField doesn't understand.

 

LOL, someone (a member of my Ignore list) is saying that I don't understand the science???
That would be weird, for a career scientist with two doctoral degrees, 41 years of experience, and hundreds of published peer-reviewed papers (and a few international awards, too).

 

But he stayed at a Holiday Inn last night.

 

Social responsibility? What the hell are you talking about?

 

There's no reason. He just likes to stir things up.

 

Where did you see that and why is it relevant?