Scientists Discover New Clue to Chemical Origins of Life ScienceDaily (Jan. 24, 2012) Organic chemists at the University of York have made a significant advance towards establishing the origin of the carbohydrates (sugars) that form the building blocks of life. -------------------------------------------------------------------------------- See Also: Plants & Animals Cell Biology Molecular Biology Earth & Climate Geochemistry Sustainability Fossils & Ruins Origin of Life Charles Darwin Reference Humus Origin of life Biochemistry RNA A team led by Dr Paul Clarke in the Department of Chemistry at York has re-created a process which could have occurred in the prebiotic world. Working with colleagues at the University of Nottingham, they have made the first step towards showing how simple sugars -- threose and erythrose -- developed. The research is published in Organic & Biomolecular Chemistry. All biological molecules have an ability to exist as left-handed forms or right-handed forms. All sugars in biology are made up of the right-handed form of molecules and yet all the amino acids that make up the peptides and proteins are made up of the left-handed form. The researchers found using simple left-handed amino acids to catalyse the formation of sugars resulted in the production of predominately right-handed form of sugars. It could explain how carbohydrates originated and why the right-handed form dominates in nature. Dr Clarke said: "There are a lot of fundamental questions about the origins of life and many people think they are questions about biology. But for life to have evolved, you have to have a moment when non-living things become living -- everything up to that point is chemistry. "We are trying to understand the chemical origins of life. One of the interesting questions is where carbohydrates come from because they are the building blocks of DNA and RNA. What we have achieved is the first step on that pathway to show how simple sugars -- threose and erythrose -- originated. We generated these sugars from a very simple set of materials that most scientists believe were around at the time that life began."
I've actually been camped out in biochem and cell biology for the last four or five years - I love it - so fascinating!!! I practically live in Alberts - Molecular Biology of the Cell [No - politics isn't my 1st love - hell, it's not even a friend.] Anyway, I have a lot of problems with molecular evolution. I'm not an opponent of evolution, per se. It's just that the horrendously interwoven functionalities and molecular inter-dependencies that form the pathways toward the first cell are seemingly chicken and egg raised to the infinite degree. And to make matters worse, bundled into the hardware we have a rather profound code being encrypted, deciphered, and implemented. And to go even one step further, most of the molecular machinery used for the encryption, decryption, and implementation of the code are themselves results of processing portions of that code! It's like looking into the infinite regression formed by diametrically opposed mirrors.
